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Nadezda Fomina

Technologies for Medical Diagnostics – Invented for Life

"Most people say that it is the intellect which makes a great scientist. They are wrong: it is character." – Albert Einstein
Nadezda Fomina

I am a synthetic polymer chemist with a background in developing "smart" materials for drug delivery. Currently, I am a Lead Scientist at Bosch Research. Our team develops new technologies for next-generation medical diagnostics, especially for point-of-care applications. Our vision is to revolutionize healthcare by combining state-of-the-art engineering solutions in MEMS sensors, circuit design, and wireless communication, with biochemistry.

Curriculum vitae

  1. Scientist in Bioelectronics Group, Novel technologies for medical diagnostics, Bosch Research and Technology Center
  2. Postdoctoral researcher, Stimuli-responsive materials for controlled drug delivery, University of California, San Diego
  3. PhD, Studies of physico-chemical properties of conjugated polymers, University of Southern California

Selected publications

  • Methods for generating pH/ionic concentration gradient near electrode surfaces for modulating biomolecular interactions

    Johnson, C. et al. (2018)

    Methods for generating pH/ionic concentration gradient near electrode surfaces for modulating biomolecular interactions
    • Christopher Johnson, Sam Kavusi, Rajan Gangadharan, Piyush Verma, Nadezda Fomina, Habib Ahmad, Lau I Aldrich
    • US9874538
  • An electrochemical platform for localized pH control on demand

    Fomina, N. et al. (2016)

    An electrochemical platform for localized pH control on demand
    • N Fomina, CA Johnson, A Maruniak, S Bahrampour, C Lang, RW Davis, S Kavusi, H Ahmad
    • Lab on a Chip, vol 16(12), pp. 2236-2244
  • Low power upconverted near‐IR light for efficient polymeric nanoparticle degradation and cargo release

    Vigel, M. et al (2013)

    Low power upconverted near‐IR light for efficient polymeric nanoparticle degradation and cargo release
    • Mathieu L Viger, Madeleine Grossman, Nadezda Fomina, Adah Almutairi
    • Advanced Materials, vol 25(27), pp.3733-3738
  • Single UV or Near IR triggering event leads to polymer degradation into small molecules

    De Gracia Lux, C. et al. (2012)

    Single UV or Near IR triggering event leads to polymer degradation into small molecules
    • Caroline de Gracia Lux, Cathryn L McFearin, Shivanjali Joshi-Barr, Jagadis Sankaranarayanan, Nadezda Fomina, Adah Almutairi
    • ACS Macro Letters, vol 1(7), pp. 922-926

Interview with Nadezda Fomina

Nadezda Fomina

Lead Scientist in Bioelectronics Group

Please tell us what fascinates you most about research.
I enjoy working in a research environment every single day. It is like solving puzzles, and I love puzzles. Together with my team, we generate and test new ideas, discuss data, find solutions to technical problems, and learn something new every day through this process.

What makes research done at Bosch so special?
At Bosch, we have access to competencies in core engineering fields such as sensors, actuators, and even packaging, which can be leveraged for medical device development. Access to medical experts through Bosch Hospital ensures that we only pursue those ideas which are truly needed in the medical field and will be adopted and used by doctors.

What research topics are you currently working on at Bosch?
Our group's research is focused on combining biology and electronics in order to improve medical diagnostics. Quantitative, low-cost detection of biomolecules with improved selectivity and specificity is a major need in healthcare. We take advantage of the sophisticated control routines and advanced data processing algorithms that are commonplace in electronics and bring those benefits into the highly-complex environment of DNA and protein measurements in order to provide more accurate and faster test results to doctors and patients.

What are the biggest scientific challenges in your field of research?
The biggest challenge in medical diagnostics is automation. Automation has the potential to dramatically reduce the cost of diagnostic tests, as well as to significantly improve their accuracy and reproducibility, which will ultimately improve patients' outcomes.

How do the results of your research become part of solutions "Invented for life"?
We strive to develop robust, state-of-the-art engineering solutions with the aim of improving people's health.

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Nadezda writes for the Bosch Research Blog. Check out her latest article:

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Nadezda Fomina
Lead Scientist in Bioelectronics Group

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